THE PARIS® TEST
More information from living cancer cells.
The PARIS Test combines functional drug testing with molecular profiling to provide personalized information about how an individual patient’s cancer may respond to potential therapies.
WHAT IS THE PARIS TEST?
See what cancer cells actually do.
Every cancer is different. Genomic testing can identify alterations in a tumor’s DNA that may help inform treatment decisions. But genetics alone does not always reveal how an individual patient’s cancer will respond to therapy.
PARIS adds another source of information by testing living tumor cells against multiple therapies and observing their response. These functional results are considered alongside molecular information to provide a more personalized picture of the cancer.
TWO COMPLEMENTARY SOURCES OF INFORMATION
Look at the cancer from more than one direction.
Explore selected research highlighting the scientific foundation, clinical application and ongoing development of functional precision oncology and the PARIS platform.
GENOMIC TESTING
What alterations are present?
Molecular profiling looks for alterations in the tumor that may provide information about potential treatment options.
FUNCTIONAL TESTING
How do living cancer cells respond?
Functional testing exposes living tumor cells to potential therapies and directly measures their response.
Together, molecular profiling and functional testing provide complementary information about the biology and behavior of an individual patient’s cancer.
FROM SAMPLE TO INSIGHT
Testing the cancer cells response. Testing cancer cells outside the patient’s body.
PARIS uses living tumor cells from a fresh tumor sample to evaluate response to multiple therapies.
1 – SAMPLE
Collect the tumor sample
A fresh tumor sample is collected and sent for testing.
2 – PREPARE
Prepare the living cells
Functional testing exposes living tumor cells to potential therapies and directly measures their response.
3 – TEST
Test potential therapies
The cells are exposed to multiple therapies under controlled laboratory conditions.
4– ANALYZE
Measure the response
The response of the living tumor cells is measured and analyzed alongside molecular information.
5 – REPORT
Provide the results
Results are provided to the treating physician to help inform the treatment conversation.
WHEN TO CONSIDER PARIS
When more information may matter.
PARIS may be considered when a patient and physician are looking for additional personalized information to help evaluate treatment possibilities.
Recurrent or Progressive Cancer
When cancer has returned or progressed despite previous treatment.
Limited Standard Options
When established treatment options are limited.
Rare Cancer
When available evidence or standard treatment pathways may be limited.
More Insight
When additional information about the individual cancer may help support a treatment conversation.
THE PARIS REPORT
Information to support the treatment conversation.
PARIS provides information about the observed response of a patient’s living tumor cells to therapies tested in the laboratory.
The functional results can be considered alongside molecular findings and other clinical information as the physician and patient evaluate potential treatment options.
PARIS provides additional information to support clinical decision-making; treatment decisions remain with the patient and their treating physician.
FOR PHYSICIANS >
AVAILABLE FOR CLINICAL USE
Advanced testing within reach.
The PARIS Test is available for clinical use through a CLIA-certified laboratory and is available to patients in all 50 states
CLIA CERTIFIED LABORATORY
50 States
Live Tumor Cells
When available evidence or standard treatment pathways may be limited.
YOUR NEXT STEP
Find the information that’s right for you.
Learn whether PARIS may be relevant to your situation, what to expect from testing and how to start a conversation with your care team.
Patients & Families
Learn whether PARIS may be relevant to your situation, what to expect and how to start a conversation with your physician.
FOR PATIENTS AND FAMILIES >
Physicians
Explore clinical evidence, patient eligibility, sample requirements and resources for ordering or referring a patient.